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Post by lilpondarosamini on Feb 27, 2007 1:52:19 GMT -5
I am trying to find out where and how to get some of my horses tested for LWO and to find out their genitics? Would someone please let me know something as to what is involved and the cost of researching? I would like to find something out about them before long. Thank you for all the info you are willing to share.
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Post by Heather T on Feb 27, 2007 2:31:20 GMT -5
www.equinetesting.com/Equine.htm Is who I use, and who I used on Prince. Their pricing is all listed there on the downloadable forms.
Stephanie with Windsong/Elements is a good one to talk to about color and what to test for. It was the Tobiano gene that I checked with Prince to find out of if he was homozygous....
All you have to do is download and print the form, collect hair samples (with roots), tape to the form -add your money and send it off. It's pretty painless, except for the price.
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Post by lilpondarosamini on Feb 27, 2007 2:53:43 GMT -5
Thank you so much. I guess I need to get him (Prince) LWO tested also as I know it would break my heart to have a LWO baby born.
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Post by Heather T on Feb 27, 2007 4:16:44 GMT -5
Are you sure he wasn't tested? There's nothing on that certificate for LWO??? I could have sworn that there was...mmm
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Post by Steph @ Elements on Feb 27, 2007 5:56:31 GMT -5
Another excellent labratory for testing is the Veterinary Genetics Lab at UC Davis - www.vgl.ucdavis.edu/ They offer online payent and form printing, and the combination of red factor and agouti is just $40. ;D As for LWO, a carrier bred to a non-carrier is fine. Some people will even risk a carrier to a carrier as you only have a 1 in 4 chance of a foal that will die. To me, those statistics are too high, but some people still do it. Some people will try to tell you that ALL frame overos carry the LWO, but this is NOT TRUE! We had a classic frame overo mare here that we had tested and she was clear, plus we know of a number of others owned by friends that have also tested clear. If you call and speak with a geneticist, they will tell you this as well. The mutation that occurs on the genome is not actually the gene that causes the fram overo pattern, but rather one that is closely located on the gene. The way the labs test for a gene is they determine first identify the location of the gene they wish to test for. Ideally, they will then find a unique pattern within that gene, but sometimes the unique pattern is just CLOSE to that gene. They creat a "molecule" that will recognize that unique pattern and bind to it (and nothing else) and they then "label" that molecule with a chemical that their machine can read. (Please tell me if I am being too vague - trying NOT to be the scientist geek here - which I am! ;D ) The Tobiano test is one where the unique pattern is only CLOSE to the actual gene. This is why they tell you that your horse is LIKELY to be homozygous, but not 100%. I had a mare that we tested TWICE as homozygous (by 2 different laboratories) and yet she had a solid foal last year. Obviously, she was the 1%... LOL Steph
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Post by lilpondarosamini on Feb 27, 2007 13:55:59 GMT -5
There is LWO Neg on Prince and I assumed that ment he was negative. Tyson is whom I want to get tested. And I have a Mare whom I knows 1/2 sister is LWO Positive so I wanted to get her checked. I just knew you knew about all this and I didnt know even where to start.
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Post by lilpondarosamini on Feb 27, 2007 14:04:07 GMT -5
I am fasinated by all the genetics of this and just want to be careful and be a responsible breeder. I realize to do this takes knowledge of the horse as well as the genetics. So all information is truly appreciated.
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Post by Heather T on Feb 27, 2007 17:25:21 GMT -5
I was always told that if the horse is a pinto or has any white on them - you have them tested, period. However, I have a friend who owns a son of my stallion, Hot Shot - that horse is solid black and threw a lethal white this past year. They searched and found four white hairs on his back (lacing)...just like his daddy. Who would have thunk it?
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Post by Steph @ Elements on Feb 27, 2007 19:58:10 GMT -5
This is sort of like people thinking that if a horse isn't an Arabian, they can't carry SCID! But my vet in Tucson treated an Apaloosa colt that DIED and was POSITIVE for SCID (homozygous).
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Post by lilpondarosamini on Feb 28, 2007 2:18:27 GMT -5
I do appreciate the honesty and plan to have them tested for LWO even if I don't have them tested for anything else. What is known of Leathel Roan babies?
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kitcat0601
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Post by kitcat0601 on May 4, 2007 6:03:45 GMT -5
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bndranch
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Post by bndranch on May 4, 2007 10:31:46 GMT -5
Without seeing the rest of the body it is hard to tell. What does his face look like? What about his legs and the white? More then one gene can play havoc on the sabino gene ie frame, or splash. Full body shot would be great!
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kitcat0601
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Post by kitcat0601 on May 4, 2007 15:04:33 GMT -5
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bndranch
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Post by bndranch on May 4, 2007 15:26:21 GMT -5
Yes very nice tushie LOL Okay here is what I have learned LOL *Sabino likes all white legs so if you have a dark leg there is another gene playing a role here. *His markings strike me as being sabino yes. Jagged edges with the roaning apparence. *His face extends past the nasal bones and he has lower lip white. *He has color in his whites (frames typically DO NOT have the dark in the white).
I would defianately have him tested but he appears Sabino to me, however there are a few others here that know more about sabino then me. I am still learning!!! The other thing you said if he is positive for OLW you said you would geld him.....why? There is nothing genetically wrong with a positive lethal white. They live normal lives. If you truely want to keep him a colt a positive OLW should not stop you. You are safe to breed a neg lethal to a positive lethal and the foal will not be a lethal white, the foal MAY CARRIER the OLWG but will not be born a lethal white. It is a common misconception about the lethal whites. Now say HYPP if you have a positive carrier there is SOMETHING that CAN physically go wrong with them so yes I will not breed any horse with a n/h statuss, however a positive carrier of the OLWG nothing will happen unless bred with another postive carrier of the OLWG and then its 25% of the time (not odds that I am willing to take.....BUT some will).
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bndranch
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Post by bndranch on May 4, 2007 15:27:53 GMT -5
I do appreciate the honesty and plan to have them tested for LWO even if I don't have them tested for anything else. What is known of Leathel Roan babies? I have never heard the term lethal roan before.
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